Knowledge, attitude, and practice of coronary heart disease patients towards antithrombotic therapy
Yingqiang Du1, Xingyou Cai1, Xin Hong1
1Department of Cardiology, Suzhou Municipal Hospital, Gusu School, the Affiliated Suzhou Hospital of Nanjing Medical University, Nanjing Medical University, Suzhou, Jiangsu Province, 215000, China.
Insights
Coronary heart disease patients have good attitudes and practices but median knowledge regarding antithrombotic therapy. Improving patient knowledge, especially in rural areas, is vital for better adherence and outcomes.
Area of Science:
- Cardiology
- Public Health
- Patient Education
Background:
- Antithrombotic therapy is critical for managing coronary heart disease (CHD).
- Understanding patient Knowledge, Attitude, and Practice (KAP) is essential for effective treatment adherence.
- This study assesses KAP regarding antithrombotic therapy in CHD patients.
Purpose of the Study:
- To evaluate the Knowledge, Attitude, and Practice (KAP) of coronary heart disease (CHD) patients concerning antithrombotic therapy.
- To identify factors influencing KAP and self-efficacy in this patient population.
- To inform targeted interventions for improving antithrombotic therapy adherence.
Main Methods:
- A cross-sectional study involving 639 CHD patients.
- Data collected via questionnaires assessing demographic information, KAP scores, and self-efficacy using the Self-Efficacy for Appropriate Medication Use Scale (SEAMS).
- Statistical analysis to identify correlations and predictive factors for KAP and self-efficacy.
Main Results:
- Median KAP scores indicated adequate attitude and practice but only moderate knowledge, particularly regarding dosage, administration, importance, and side effects of antithrombotic agents.
- Approximately 70% of patients had incorrect knowledge about dosage/administration, and 40% were unaware of treatment importance/side effects.
- Low practice scores were associated with rural residence, low attitude scores, and poor self-efficacy. Low self-efficacy was linked to being underweight, high family income, short medical history, and low attitude scores.
Conclusions:
- CHD patients demonstrate a gap in knowledge about antithrombotic therapy, despite positive attitudes and practices.
- Interventions should prioritize enhancing knowledge, especially for rural populations, to improve adherence.
- Improving patient KAP can foster better physician-patient communication and therapeutic outcomes.
Background:
The role of antithrombotic therapy in prognosticating patients with coronary heart disease (CHD) is crucial. This study evaluated the Knowledge, Attitude, and Practice (KAP) of CHD patients regarding antithrombotic therapy.
Methods:
This cross-sectional study distributed questionnaires to collect data. Participants' demographic information was recorded, and their KAP scores were assessed. The Self-Efficacy for Appropriate Medication Use Scale (SEAMS) measured self-efficacy.
Results:
The study comprised 639 individuals. The median scores were as follows: knowledge score 8 (IQR 6-10), attitude score 25 (IQR 23-27), and practice score 22 (IQR 20-24). Notably, up to 70% of patients incorrectly responded to questions about dosage and administration of antithrombotic agents, and approximately 40% lacked awareness of the treatment's importance and side effects. Low practice scores were independently linked to rural residence, low attitude scores, and poor self-efficacy. Furthermore, Predictive factors for low self-efficacy included being underweight, having a high family income, a short medical history, and low attitude scores.
Conclusions:
The surveyed patients with CHD exhibited good attitudes, practices, and self-efficacy but demonstrated only median knowledge levels toward antithrombotic therapy, especially about the importance and precautions associated with antithrombotic treatment. Therefore, initiatives aimed at improving adherence to antithrombotic therapy among CHD patients should focus on the knowledge gaps, especially for patients in rural areas. Improving the patient KAP could help improve the physician-patient interaction.
Related Concept Videos
01:20Antiplatelet Drugs: Prostaglandin Synthesis, P2Y12 and Glycoprotein IIb/IIIa Inhibitors
Prostaglandin synthesis inhibitors, exemplified by the widely known aspirin, wield their power by irreversibly acetylating...
01:18Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
01:17Ischemic Heart Disease: Overview
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
01:23Assessment of the Cardiovascular System I: Subjective Data
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
01:30Anticoagulant Drugs: Low-Molecular-Weight Heparins
01:26Treatment for Pulmonary Arterial Hypertension: Receptor Tyrosine Kinase Inhibitors and Calcium Channel Blockers
TKIs, such as imatinib (Gleevec), are particularly effective in tackling the growth and mitogenic factors that become upregulated in PAH patients. These factors contribute to the...