Related Experiment Video
Updated: May 28, 2025

07:51
Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
1.5K
Tomographic characteristics of thick corneas
Junjie Yu1,2, Ye Xu1,2, Xiaoying Wang1,2
1Department of Ophthalmology, Eye and ENT Hospital, Fudan University, No. 83, Fenyang Rd, Xuhui Dist, Shanghai, People's Republic of China.
BMC Ophthalmology
|February 10, 2025
Summary
Thick corneas show distinct tomographic features, including increased back elevation and deviation of normality, impacting refractive surgery assessments. These findings highlight the importance of detailed corneal analysis in surgical candidates.
Area of Science:
- Ophthalmology
- Corneal Tomography
- Refractive Surgery
Background:
- Corneal thickness is a critical factor in refractive surgery candidacy.
- Understanding tomographic characteristics of thicker corneas is essential for accurate pre-operative assessment.
Purpose of the Study:
- To analyze tomographic features of excessively thick corneas.
- To evaluate the influence of these features on refractive surgery candidate screening.
Main Methods:
- Corneal tomography was performed on three groups of eyes based on thinnest pachymetry (TP): <500 μm, 500–580 μm, and ≥580 μm.
- Pentacam ectasia indices were compared across these groups.
Main Results:
- Eyes with TP ≥580 μm exhibited significantly higher back elevation (BE) and deviation of normality of the back elevation (Db), and a more negative Q value for the back surface (Qback) compared to those with TP 500–580 μm.
- No significant differences were found in anterior corneal indices between the groups.
- Abnormalities in BE and Db were most prevalent in the thickest cornea group (TP ≥580 μm).
Conclusions:
- Tomography of thick corneas reveals specific posterior surface abnormalities (BE, Db, Qback).
- Anterior corneal indices do not significantly differ in thick corneas.
- These tomographic findings are crucial for the accurate assessment of refractive surgery candidates with thicker corneas.

