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Long-term Home Mechanical Ventilation of Children in İstanbul

Mürüvvet Yanaz1, Füsun Ünal2, Evrim Hepkaya3

  • 1Department of Pediatric Pulmonology, Marmara University Faculty of Medicine, İstanbul, Türkiye.

Thoracic Research and Practice
|February 11, 2025
PubMed

Insights

Half of children on long-term home mechanical ventilation (HMV) received invasive support, with higher risks of continuous ventilation, oxygen, and hospitalization. This study characterized HMV use in İstanbul.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Critical Care

Background:

  • Home mechanical ventilation (HMV) is crucial for children with chronic respiratory failure.
  • Understanding patient characteristics and ventilation modalities is essential for optimizing care.

Purpose of the Study:

  • To describe the characteristics of children receiving long-term HMV in İstanbul.
  • To compare non-invasive ventilation (NIV) and invasive ventilation (IV) in this pediatric population.

Main Methods:

  • Cross-sectional multicenter study of 416 children receiving long-term HMV.
  • Data collected from patient charts between May 2020 and May 2021.
  • Demographic and HMV data analyzed.

Main Results:

  • Most common diagnoses: neuromuscular (35.1%) and neurological (25.7%).
  • 49.5% received NIV, 50.5% received IV. IV patients were younger at initiation and more likely to need continuous support and oxygen.
  • 59.1% were hospitalized in the last year; risk factors included IV, continuous support, oxygen, tube feeding, and swallowing dysfunction.

Conclusions:

  • Despite increasing NIV use, half of pediatric HMV patients received invasive ventilation.
  • Invasive ventilation was associated with greater need for continuous support, oxygen supplementation, and increased hospitalization risk.
Abstract

Keywords:
Non-invasive ventilationchronic respiratory failurelong-term home mechanical ventilationneuromuscular disorders,

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