Au(I)-, Au(II)-, Au(III)-Fluoride Complexes: Synthesis and Applications in Organic Transformations

Area of Science:

• Organometallic Chemistry
• Fluorine Chemistry
• Catalysis

Background:

• Organometallic gold-fluoride complexes were historically elusive due to instability.
• Despite advances in gold catalysis, these specific complexes remained largely uncharacterized.
• Recent years have seen a surge in reports on these compounds.

Purpose of the Study:

• To review the synthesis and reactivity of organometallic gold-fluoride complexes.
• To cover developments up to and including 2024.
• To organize findings by gold oxidation state and supporting ligand.

Main Methods:

• Literature review of published research on gold-fluoride complexes.
• Analysis of synthetic strategies and reactivity studies.
• Categorization of complexes based on gold oxidation state (Au(I), Au(II), Au(III)) and ligand environment.

Main Results:

• Several reports detailing the synthesis and characterization of gold-fluoride complexes have emerged.
• The use of diverse supporting ligands has been crucial for accessing these unstable species.
• Reactivity studies have elucidated their potential in various transformations.

Conclusions:

• Organometallic gold-fluoride complexes are now accessible and their chemistry is increasingly understood.
• These complexes show promise for developing novel C-C and C-F coupling reactions.
• Further research into ligand design and reactivity will drive future applications in catalysis.