Deep learning for RNA structure prediction
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Updated: May 28, 2025

Probing RNA Structure with Dimethyl Sulfate Mutational Profiling with Sequencing In Vitro and in Cells
Published on: December 9, 2022
Jiuming Wang1, Yimin Fan1, Liang Hong1
1Department of Computer Science and Engineering, The Chinese University of Hong Kong, Hong Kong SAR, China.
Abstract:
Predicting RNA structures from sequences with computational approaches is of vital importance in RNA biology considering the high costs of experimental determination. AI methods have revolutionized this field in recent years, enabling RNA structure prediction with increasingly higher accuracy and efficiency. With an increase in the number of models proposed for this task, this review presents a timely summary of the applications of AI, particularly deep learning, in RNA structure prediction, highlighting their methodology advances as well as the challenges and opportunities for further work in this field.
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