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Updated: May 6, 2026
Optimized PCR-based Detection of Mycoplasma
Published on: June 20, 2011
Panoramic quantitative and visualization-based bibliometric analysis of Mycoplasma pneumoniae
1Department of Laboratory Medicine, Tongji Medical College, Wuhan Children's Hospital (Wuhan Maternal and Child Healthcare Hospital), Huazhong University of Science & Technology, Wuhan, Hubei, 430016, P.R. China.
Purpose:
Severe pneumonia, refractory pneumonia and extrapulmonary complications caused by mycoplasma pneumoniae infection were increasing, posing a serious threat to health. This study aimed to explore a breakthrough for further investigations in further.
Methods:
The Web of Science Core Collection was queried using the search term TS = "mycoplasma pneumoniae" for articles from January 1, 2009, to September 24, 2024. Bibliometric indicators were analyzed using VOSviewer, Pajek, and Scimago Graphica, while CiteSpace was utilized for visual analyses, including the contributions of different countries/regions, institutions, authorship patterns, journals, co-citations, keywords, and genes.
Results:
3,093 articles were collected and showed an increase interest in MPP research. China was the most prolific contributor, and the USA demonstrated the strongest collaboration willingness. The USA and China had the highest cooperation frequency and closest research relationship. The UK had the highest single-article citation count. Fudan University had the greatest total link strength. The top keywords were "Mycoplasma Pneumoniae" and "community-acquired pneumonia", with "children" being particularly prominent throughout the literatures. "risk factors" and "plastic bronchitis" may represent emerging hotspots in MPP research. Antibiotic therapy, herpes simplex virus infections, and serology detection were the high interest surrounding topics over past decade. mNGS, severe community-acquired pneumonia, co-infections of adenovirus or RSV may become focal points in future. CRP and IL-17 A represented significant genes among MP infection. Positive regulation of cytokine production played a critical role in MP infection.
Conclusion:
This bibliometric analysis provides insights into its status, frontiers, and hotspots, offering essential guidance to address challenges in MP.
Insights
Mycoplasma pneumoniae research is growing, with China leading publications and the USA leading collaborations. Key areas include pediatric community-acquired pneumonia, risk factors, and emerging diagnostics like mNGS.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Public Health
Background:
- Mycoplasma pneumoniae infections are increasingly associated with severe pneumonia, refractory cases, and extrapulmonary complications.
- These infections pose a significant and growing threat to public health globally.
- Understanding research trends is crucial for developing effective strategies against Mycoplasma pneumoniae.
Purpose of the Study:
- To conduct a bibliometric analysis of Mycoplasma pneumoniae research.
- To identify key contributors, collaboration patterns, and research hotspots.
- To provide insights for future research directions and clinical management.
Main Methods:
- Bibliometric analysis of 3,093 articles from Web of Science Core Collection (2009-2024).
- Utilized VOSviewer, Pajek, and Scimago Graphica for indicator analysis.
- Employed CiteSpace for visual analysis of countries, institutions, authors, journals, co-citations, keywords, and genes.
Main Results:
- China led in publications, while the USA showed the strongest collaboration willingness and highest cooperation frequency.
- The UK had the highest single-article citation count; Fudan University demonstrated the greatest total link strength.
- Prominent keywords included "Mycoplasma Pneumoniae" and "community-acquired pneumonia," with a focus on "children." Emerging hotspots include "risk factors" and "plastic bronchitis."
Conclusions:
- This bibliometric analysis highlights the current status, frontiers, and hotspots in Mycoplasma pneumoniae research.
- Findings offer essential guidance for addressing challenges posed by Mycoplasma pneumoniae infections.
- Future research may focus on mNGS, severe pneumonia, co-infections, and specific genetic/cytokine pathways.
