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Prevalence, numbers and mortality risk of hypertensive patients with depressive symptom in China

Shufeng Li1, Ting Xu2, Haixiu Wen3

  • 1Department of Preventive Medicine, Fenyang College of Shanxi Medical University, Fenyang, 032200, Shanxi, China. shufengli@sxmu.edu.cn.

BMC Cardiovascular Disorders
|February 11, 2025
PubMed

Insights

Over 72 million adults in China have both hypertension and depressive symptoms, facing low treatment rates and a doubled risk of mortality. Integrated care strategies are crucial for managing these coexisting conditions.

Area of Science:

  • Public Health
  • Cardiology
  • Psychiatry

Background:

  • China faces a growing burden of hypertension and depression.
  • Co-occurrence of these conditions poses significant health challenges.

Purpose of the Study:

  • Assess the prevalence and population size of adults with both hypertension and depressive symptoms in China.
  • Evaluate the risk of all-cause mortality associated with this comorbidity.

Main Methods:

  • Utilized data from the China Health and Retirement Longitudinal Study (CHARLS).
  • Employed Cox proportional hazard models to analyze mortality risk.
  • Estimated prevalence, treatment recommendation rates, and blood pressure control rates.

Main Results:

  • 15.01% of Chinese adults (72.06 million) have both hypertension and depressive symptoms.
  • Low adherence to medication recommendations and suboptimal blood pressure control were observed.
  • Hypertension with depressive symptoms significantly increased all-cause mortality risk (HR=2.21).

Conclusions:

  • A substantial number of Chinese adults suffer from comorbid hypertension and depression with inadequate management.
  • The combination of hypertension and depression elevates mortality risk.
  • Integrated strategies for hypertension and depression care are essential.
Abstract

Keywords:
All-cause mortalityDepressionHypertensionNumberPrevalence

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