Related Experiment Video
Updated: Jun 13, 2025
In Vitro Methods for Comparing Target Binding and CDC Induction Between Therapeutic Antibodies: Applications in Biosimilarity Analysis
Published on: May 4, 2017
[Efficacy of rituximab for idiopathic acquired pure red cell aplasia]
Shuku Sato1, Shun Tsunoda1, Yotaro Tamai1
1Division of Hematology, Shonan Kamakura General Hospital.
Abstract:
Primary acquired pure red cell aplasia (PRCA) is associated with reticulocytopenia and a significant decrease in bone marrow erythroblasts. We describe three patients with refractory idiopathic PRCA treated with rituximab. Two were transfusion-dependent and unresponsive to various immunosuppressive therapies, and were successfully weaned off transfusion following rituximab therapy. The patient who was unresponsive to rituximab achieved remission on cyclosporine but subsequently relapsed. This is the first case report from Japan to describe the effectiveness of rituximab for refractory idiopathic PRCA.
More Related Videos
11:59Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
05:23Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
Published on: March 14, 2017
Related Concept Videos
01:22Bone Marrow Sampling and Transplants
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
01:19Rh Blood Group
02:45Blood Transfusion and Agglutination
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...