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Updated: May 28, 2025

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
Published on: August 2, 2021
Diagnosis of depression based on facial multimodal data
Nani Jin1, Renjia Ye1, Peng Li2
1Materdicine Lab, School of Life Sciences, Shanghai University, Shanghai, China.
Introduction:
Depression is a serious mental health disease. Traditional scale-based depression diagnosis methods often have problems of strong subjectivity and high misdiagnosis rate, so it is particularly important to develop automatic diagnostic tools based on objective indicators.
Methods:
This study proposes a deep learning method that fuses multimodal data to automatically diagnose depression using facial video and audio data. We use spatiotemporal attention module to enhance the extraction of visual features and combine the Graph Convolutional Network (GCN) and the Long and Short Term Memory (LSTM) to analyze the audio features. Through the multi-modal feature fusion, the model can effectively capture different feature patterns related to depression.
Results:
We conduct extensive experiments on the publicly available clinical dataset, the Extended Distress Analysis Interview Corpus (E-DAIC). The experimental results show that we achieve robust accuracy on the E-DAIC dataset, with a Mean Absolute Error (MAE) of 3.51 in estimating PHQ-8 scores from recorded interviews.
Discussion:
Compared with existing methods, our model shows excellent performance in multi-modal information fusion, which is suitable for early evaluation of depression.
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Facial Feedback Hypothesis
Depression: Overview

