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A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Homemade stent shields: fortifying against coronary perforation in STEMI patients amidst intensive glycoprotein
Muhammad Imran Hanif1, Minahil Tariq Sheikh1
1Department of Cardiology, Gulab Devi Chest Hospital, Ferozepur Road, Lahore 54000, Pakistan.
Insights
Coronary artery perforation (CAP) during percutaneous coronary intervention (PCI) can be managed with an improvised covered stent when commercial options are unavailable. This case demonstrates the feasibility and safety of this novel approach in a STEMI patient.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
- Medical Device Innovation
Background:
- Coronary artery perforation (CAP) is a rare but serious complication during percutaneous coronary intervention (PCI).
- Prompt management is crucial, typically involving covered stents to seal the perforation.
- Improvised covered stents offer an alternative when commercial devices are unavailable.
Observation:
- A 70-year-old male with myocardial infarction underwent primary PCI.
- The procedure resulted in CAP, leading to cardiac tamponade, managed with pericardiocentesis.
- A commercial covered stent was unavailable; an improvised one was successfully deployed.
Findings:
- The improvised covered stent effectively sealed the coronary artery perforation.
- The patient received glycoprotein IIb/IIIa inhibitors and heparin for acute stent thrombosis.
- Hemodynamic status stabilized, and the patient was discharged in stable condition.
Implications:
- This case highlights the feasibility and safety of using homemade covered stents in managing CAP.
- Improvised stenting techniques may be a viable option in complex PCI, especially in resource-limited settings.
- Further research could validate this approach, expanding treatment options for coronary artery perforation.
Background:
Coronary artery perforation (CAP), though rare, is a serious complication of percutaneous coronary intervention (PCI) that demands prompt, tailored management. Swift recognition and intervention are essential. Typically, a covered stent is used to seal the perforation and restore vessel integrity. However, if unavailable, a homemade covered stent can be crafted and deployed. The choice of treatment depends on bleeding severity, patient stability, and available resources.
Case Summary:
A 70-year-old male with a history of diabetes and hypertension presented with severe chest pain persisting for 7-8 h, radiating to the left arm and jaw, accompanied by diaphoresis and nausea. His baseline electrocardiogram revealed an extensive anterior wall myocardial infarction, prompting immediate transfer to the catheterization laboratory for primary PCI. During the procedure, an unfortunate complication of CAP leading to cardiac tamponade was successfully managed by pericardiocentesis. With the unavailability of commercial covered stents, an improvised covered stent was fashioned and deployed, effectively sealing the perforation despite ongoing administration of glycoprotein IIb/IIIa inhibitors and heparin which was initiated following acute stent thrombosis. The patient's haemodynamic status stabilized during hospitalization, and he was discharged in a stable condition.
Discussion:
Our case is a pioneering instance of using a homemade stent with glycoprotein IIb/IIIa inhibitors and heparin in a STEMI patient with CAP. This novel approach was successful, demonstrating its feasibility and safety. Our experience suggests that improvised stenting techniques could be a viable option in complex coronary interventions, especially when commercial alternatives are unavailable. Further validation may broaden treatment options and improve outcomes in interventional cardiology.
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