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DRP1: shedding light on the complex nexus of mitochondrial fission and breast cancer
Li You1, Min Wang1, Xuexue Liu1
1Department of Laboratory Medicine, The Affiliated Hospital of Southwest Medical University. Sichuan Province Engineering Technology Research Center of Molecular Diagnosis of Clinical Diseases. Molecular Diagnosis of Clinical Diseases Key Laboratory of Luzhou, Sichuan, China.
Abstract:
Breast cancer (BC) is a global women's health concern, with ongoing research to address diagnostic and treatment challenges. Understanding the developmental mechanisms is vital for improved clinical prevention and treatment strategies. Mitochondria, undergo dynamic processes like fission and fusion, regulated by proteins like Dynamic-related protein 1 (DRP1). DRP1 plays a key role in mitochondrial fission, a process associated with BC development. This study aims to explore the impact of DRP1 on BC growth, assessing its potential as a therapeutic target. The findings could contribute to a better understanding of mitochondria-related molecular mechanisms in BC development and guide the identification of clinical drug targets.
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