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Mesoappendiceal paraganglioma.

D E Clark, J F Stocks, J L Wilkis

    The American Journal of Gastroenterology
    |May 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    A rare 10-cm paraganglioma of the mesoappendix was surgically removed from an asymptomatic patient. This case and a literature review suggest these are aberrant retroperitoneal paragangliomas.

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    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Pathology

    Background:

    • Paragangliomas are rare neuroendocrine tumors typically arising in the adrenal medulla or sympathetic chain.
    • Gastrointestinal paragangliomas are exceptionally uncommon, with most reported cases involving the stomach, duodenum, or rectum.

    Observation:

    • A 10-cm tumor of the mesoappendix, a rare location, was surgically resected from an 81-year-old asymptomatic woman.
    • The patient remained healthy 5 years post-surgery, indicating a favorable prognosis for this specific tumor type and location.

    Findings:

    • Histological examination confirmed the tumor as a paraganglioma.
    • A review of five additional case reports of paraganglioma in the gastrointestinal tract distal to the duodenum was conducted.

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    Implications:

    • The authors propose that these rare gastrointestinal paragangliomas, particularly those in the mesoappendix, should be classified as aberrant retroperitoneal paragangliomas.
    • This classification may aid in understanding their embryological origin and guide future diagnostic and treatment strategies.