Related Experiment Video
Updated: Jul 8, 2026
08:52
Modeling Osteosarcoma Using Li-Fraumeni Syndrome Patient-derived Induced Pluripotent Stem Cells
Published on: June 13, 2018
8.8K
Systemic Sclerosis Complicated by Rapidly Progressive Osteomyelitis: A Case Report
1Department of Rheumatology of Lucania, UOSD of Rheumatology, "Madonna delle Grazie" Hospital, Matera, Italy.
Current Rheumatology Reviews
|February 12, 2025
Summary
Systemic sclerosis patients with vascular issues need careful monitoring for osteomyelitis. Early antibiotic treatment is key to preventing severe bone damage and improving outcomes in these rare cases.
Area of Science:
- Rheumatology
- Infectious Diseases
- Vascular Medicine
Background:
- Systemic sclerosis (SSc) is an autoimmune disease causing fibrosis and vascular problems.
- Osteomyelitis is a rare but severe complication in SSc patients, especially with poor circulation.
- This case emphasizes rapid osteomyelitis progression and the need for prompt management.
Related Concept Videos
01:26Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
01:19Multiple Sclerosis l: Introduction
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...