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Updated: May 28, 2025

Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
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Causal association between polyunsaturated fatty acids and acne: a two-sample Mendelian randomization study

Bo Ri Kim1,2, Gahyun Kim3, Seon-Pil Jin2,4

  • 1Department of Dermatology, Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

The British Journal of Dermatology
|February 12, 2025
PubMed
Summary

High docosahexaenoic acid (DHA) levels protect against acne, while high linoleic acid (LA) and omega-6:omega-3 ratios increase acne risk. These polyunsaturated fatty acid (PUFA) effects are genetically influenced, particularly by FADS1 variants.

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