Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Working Memory01:24

Working Memory

125
Working memory refers to a combination of components, including short-term memory and attention, that allow an individual to hold information temporarily as we perform cognitive tasks. It is an essential cognitive function that enables the execution of complex tasks such as problem-solving, comprehension, and reasoning. Unlike short-term memory, which simply involves the storage of information for a brief period, working memory involves the active manipulation and processing of this...
125
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

342
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
342

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Methods for Functional Validation of Terpenoid Metabolic Clusters in Nicotiana benthamiana and Aspergillus oryzae.

Methods in molecular biology (Clifton, N.J.)·2026
Same author

Cross-Subject Event-Related Potential Classification via Multi-View Based Contrastive Learning.

Brain connectivity·2026
Same author

Associations between parental role modeling of physical activity and overweight and obesity in children and adolescents: words, actions, or both? A cross-sectional study of young children's population in Shanghai.

BMC public health·2026
Same author

Impact of a school based flag football intervention on fitness outcomes in Chinese children aged 9 to 11 years: a randomized controlled trial.

BMC public health·2026
Same author

Machine Learning-Based Classification of Alertness Levels in Elite Shooting Athletes Using Heart Rate Variability.

Journal of sports science & medicine·2026
Same author

Plant-derived extracellular vesicles for cancer therapy: Biological features, therapeutic mechanisms and pharmaceutical applications.

Colloids and surfaces. B, Biointerfaces·2026
Same journal

Benchmarking fMRI Denoising Pipelines.

Human brain mapping·2026
Same journal

Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic Circuits.

Human brain mapping·2026
Same journal

Intrinsic Functional Architecture Reflects Individual Differences in Passive Working Memory: An Exploratory Resting-State fMRI Study.

Human brain mapping·2026
Same journal

Symptom Overlap and Neurobiological Similarities Between Posttraumatic Stress Disorder and Tinnitus.

Human brain mapping·2026
Same journal

Test-Retest Reliability of Sensorimotor Activity Measured With Spinal Cord fMRI.

Human brain mapping·2026
Same journal

The Human Visual Claustrum Responses to Physical Stimulus Properties and Subjective Content During Movie Viewing.

Human brain mapping·2026
See all related articles

Related Experiment Video

Updated: May 28, 2025

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

13.7K

Temporal Interference Stimulation Boosts Working Memory Performance in the Frontoparietal Network.

Suwang Zheng1,2, Yufeng Zhang1,2, Kun Huang3

  • 1Key Laboratory of Exercise and Health Sciences of Ministry of Education, Shanghai University of Sport, Shanghai, China.

Human Brain Mapping
|February 12, 2025
PubMed
Summary
This summary is machine-generated.

Temporal interference (TI) stimulation enhances working memory by modulating brain activity and connectivity in the frontoparietal network. This novel neuromodulation technique shows promise for cognitive enhancement applications.

Keywords:
fMRIfrontoparietal networkfunctional connectivitytemporal interference stimulationworking memory

More Related Videos

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
10:38

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions

Published on: July 16, 2015

13.6K
The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents
10:27

The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents

Published on: April 19, 2019

6.9K

Related Experiment Videos

Last Updated: May 28, 2025

Transcranial Direct Current Stimulation tDCS for Memory Enhancement
10:37

Transcranial Direct Current Stimulation tDCS for Memory Enhancement

Published on: September 18, 2021

13.7K
A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions
10:38

A Cognitive Paradigm to Investigate Interference in Working Memory by Distractions and Interruptions

Published on: July 16, 2015

13.6K
The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents
10:27

The Power of Interstimulus Interval for the Assessment of Temporal Processing in Rodents

Published on: April 19, 2019

6.9K

Area of Science:

  • Neuroscience
  • Neuromodulation
  • Cognitive Science

Background:

  • Temporal interference (TI) stimulation is a non-invasive neuromodulation technique.
  • Previous research indicated TI stimulation enhances working memory (WM) performance.
  • Neural mechanisms underlying TI stimulation's effects on WM remain unclear.

Purpose of the Study:

  • To investigate the neural mechanisms of offline TI stimulation on brain activity and behavior.
  • To explore how TI stimulation modulates the frontoparietal network during working memory tasks.

Main Methods:

  • Randomized, double-blind, crossover study design.
  • Task-based functional magnetic resonance imaging (fMRI) experiment.
  • TI stimulation (6 Hz, targeting MFG and IPL) versus sham stimulation.

Main Results:

  • TI stimulation significantly improved performance (d') in high-demand WM tasks.
  • Whole-brain analysis revealed reduced activation in IPL and precuneus post-TI stimulation.
  • gPPI analysis showed increased functional connectivity between MFG and IPL, correlated with improved WM performance.

Conclusions:

  • Offline TI stimulation specifically modulates brain activation and functional connectivity within the frontoparietal network.
  • TI stimulation enhances cognitive performance by altering neural network dynamics.
  • Findings offer insights for future neuromodulation applications in cognitive enhancement.