Related Experiment Video
Updated: May 6, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
Published on: January 22, 2015
Nanoemulsions base on the Rice bran albumin-sweet potato leaf polyphenol-dextran complexes: Interaction mechanisms,
Junren Wen1, Yong Sui2, Jianbin Shi2
1Key Laboratory of Agricultural Products Cold Chain Logistics, Ministry of Agriculture and Rural Affairs, Institute of Agro-Products Processing and Nuclear agricultural Technology, Hubei Academy of Agricultural Sciences, Wuhan 430064, China; College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Abstract:
In this study, rice bran albumin (RBA), sweet potato leaf polyphenols (SPLPs) and dextran were conjugated through covalent or non-covalent interactions to improve the stability and bioaccessibility of astaxanthin (AST) in emulsion systems. It was shown that the RBA-SPLPs-Dex ternary covalent complex demonstrated higher polysaccharide grafting, looser secondary structure, and exposed hydrophobic groups indicating that they were favourable for emulsion stabilisation. In long-term storage tests, RBA-SPLPs emulsifier modified by 50 mg/mL dextran (Dextran50) showed smaller particle size and cream index, respectively. Besides, the retention of loaded astaxanthin was improved by 59.43 % compared to the unmodified model, along with a strengthened inhibition of lipid oxidation in the storage experiment. Besides, Dextran50 also improved the environmental stress stability of the emulsion and demonstrated more efficient AST release behaviour during intestinal digestion. In conclusion, these emulsion systems stabilised with ternary complexes have great potential for the delivery of lipid-soluble bioactive ingredients.
Related Concept Videos
Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry
Bioavailability Enhancement: Drug Solubility Enhancement
Bioavailability Enhancement: Drug Permeability Enhancement
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention

