Partial proteolytic protein maps: Cleveland revisited

Low concentrations of sodium dodecyl sulfate have a dramatic effect on the partial proteolytic products obtained by digesting bovine serum albumin with chymotrypsin or trypsin. The effect observed may be important for the interpretation of peptide maps obtained by the method of D. W. Cleveland et al. [(1977) J. Biol. Chem. 252, 1102-1106].