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Published on: November 12, 2015
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Topographic Pattern-Based Nomogram to Guide Keraring Implantation in Eyes with Mild to Moderate Keratoconus: Visual
Ugo de Sanctis1,2,3, Paolo Caselgrandi1, Carlo Gennaro1
1Section of Ophthalmology, Department of Surgical Sciences, University of Turin, 10126 Turin, Italy.
Journal of Clinical Medicine
|February 13, 2025
Summary
Keraring implantation guided by a topographic nomogram significantly improved uncorrected and corrected distance visual acuity in mild to moderate keratoconus patients. This safe and effective approach enhances vision and reduces corneal aberrations.
Area of Science:
- Ophthalmology
- Corneal Surgery
- Vision Science
Background:
- Keratoconus is a progressive corneal ectasia causing visual impairment.
- Mild to moderate keratoconus requires effective treatment strategies to improve visual outcomes.
- Keraring implantation is a surgical option for managing keratoconus.
Purpose of the Study:
- To evaluate the efficacy and safety of Keraring implantation using a topographic pattern-based nomogram.
- To assess visual acuity and refractive outcomes after Keraring implantation.
- To analyze changes in corneal topography and aberrations post-surgery.
Main Methods:
- Retrospective analysis of 47 eyes with stage I-II keratoconus undergoing femtosecond laser-assisted Keraring implantation.
- Keraring selection guided by a topographic pattern-based nomogram.
- Preoperative and postoperative data collection including visual acuity, refraction, and Pentacam HR tomographic analysis.
Main Results:
- Significant improvement in uncorrected distance visual acuity (UDVA) by 5.13 lines (p < 0.001).
- Marked enhancement in corrected distance visual acuity (CDVA), with 85.1% of eyes achieving ≥ 20/25.
- Reduction in refractive cylinder, keratometry, and corneal high-order aberrations, including vertical coma (p < 0.001).
Conclusions:
- Topographic pattern-based nomogram-guided Keraring implantation is highly effective and safe for mild to moderate keratoconus.
- The procedure leads to clinically significant improvements in UDVA and CDVA.
- Keraring implantation effectively reduces corneal irregularities and aberrations.

