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IgG4-RD-Associated Mikulicz Syndrome Without Classic Systemic Involvement-A Case Report
Luis Ángel Mendoza-Vargas1, Samuel Sevilla-Fuentes1, Brandon Bautista-Becerril2,3
1Hospital General de Zona 1 "Emilio Varela Luján", Zacatecas 98000, Mexico.
This case study shows that IgG4-related disease (IgG4-RD) can occur with normal IgG4 levels, emphasizing histopathology for diagnosis. Early steroid treatment led to significant symptom resolution and recovery.
Area of Science:
- Immunology
- Rheumatology
- Ophthalmology
Background:
- IgG4-related disease (IgG4-RD) is a rare inflammatory condition with diverse presentations.
- Common phenotypes include pancreatic-hepatobiliary, retroperitoneal/aortic, head and neck disease, and Mikulicz syndrome.
- Mikulicz syndrome involves dacryoadenitis and orbital pseudotumor, typically seen in Asian populations.
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