Automatic Measurement of Frontomaxillary Facial Angle in Fetal Ultrasound Images Using Deep Learning

Accurate measurement of frontomaxillary facial (FMF) angles in prenatal ultrasound (US) scans plays a pivotal role in the screening of trisomy 21. Nevertheless, this intricate procedure heavily relies on the proficiency of the ultrasonographer and tends to be a time-intensive task. Furthermore, FMF angles are subjective when measured manually. To address this challenge, we propose a deep learning-based assisted examination framework for automatically measuring FMF angles on 2D ultrasound images. Firstly, we trained a deep learning network using 1549 fetal ultrasound images to achieve automatic and accurate segmentation of critical areas. Subsequently, a key point detection network was employed to predict the coordinates of the requisite points for calculating FMF angles. Finally, FMF angles were obtained through computational means. We employed Pearson correlation coefficients and Bland-Altman plots to assess the correlation and consistency between the model's predictions and manual measurements. Notably, our method exhibited a mean absolute error of 2.354°, outperforming the typical standards of the junior expert. This indicates the high degree of accuracy and reliability achieved by our approach.