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Updated: May 28, 2025

High-throughput Nitrobenzoxadiazole-labeled Cholesterol Efflux Assay
Published on: January 7, 2019
[Cholesterol level and distribution characteristics in adults aged 20 years and above in China in 2015-2017]
Fusheng Li1, Hongtao Yuan1, Mulei Chen2
1National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Objective:
To analyze the level and distribution characteristics of remnant cholesterol(RC) among Chinese adult residents.
Methods:
Data was collected from Chinese Nutrition and Health Surveillance(2015-2017). A stratified, multi-stage, random sampling method was used. A total of 135 934 residents aged 20 years and above from 31 provinces were included in this study. This study included survey data, medical examination data, and laboratory testing data. International general estimation method was used to calculate remnant cholesterol. Chi-square test was used to analysis RC level and its distribution characteristics by weighted adjustment of the sixth national population census data provided by the National Bureau of Statistics.
Results:
The level of RC showed significant spatial and population differences. The proportion of males in the high RC group was higher than that in females(14.39% vs.10.72%), and the proportion of urban residents was lower than that of rural residents(11.3% vs.13.78%). The median level of RC in South China was the highest(0.49 mmol/L). The lowest median level of RC was 0.43 mmol/L in central China. The median RC level varies among different chronic disease populations, with the highest median RC level being 0.57 mmol/L for dyslipidemia. The median RC level for hypertension and coronary heart disease is the lowest at 0.50 mmol/L. Additionally, the median RC levels of various chronic diseases in females are significantly higher than those in males.
Conclusion:
The level of RC in Chinese adult residents shows obvious population, spatia, and chronic disease distribution characteristics. Taking targeted measures for key populations in key areas can effectively reduce the level of RC in the population, thereby reducing the risk of inducing cardiovascular disease.
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