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Updated: Jul 28, 2026
Photopatterning Proteins and Cells in Aqueous Environment Using TiO2 Photocatalysis
Published on: October 26, 2015
Sunscreen Formula of FeO(OH)·H2O/TiO2 With Spectral Selectivity to Enhance Collagen Biosynthesis via Fibroblast Test
Xun Zhang1, Ximing Wen1, Yuling Wang1
1Bloomage Biotech Co. Ltd., Jinan, Shandong, China.
Objective:
To develop a sunscreen formula with spectral selectivity that filters harmful light (280-550 nm) while allowing beneficial light (550-760 nm) to permeate and thus to boost collagen generation.
Methods:
A variety of sunscreen filters and their combinations were tested for transmittance spectrum. The spectral selectivity was quantified by Selection Index (SI), and the optimal formula was identified. Then, human dermal fibroblasts (HDFs) were subjected to simulated sunlight exposure with the application of this formula. The cell viability and collagen levels were measured post-exposure.
Results:
The combination of TiO2 and FeO(OH)·H2O displays spectral selectivity and reaches the optimal SI value at the mixing ratio of 64:36. This mixture, when formulated with traditional UV filters, significantly elevates the level of Collagen I.
Conclusion:
This work uncovers the influence of spectral selectivity on the enhancement of sunscreen performance and proposes a filter combination with spectral selectivity. This formula, when integrated with conventional UV sunscreens, allows for the beneficial effects of sunlight to be more pronounced. This discovery may provide fresh insights for the design of future sunscreen products.
