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Recalcitrant vulvar lichen planus cleared on abrocitinib: A case report
Celina DeBiasio1,2, Carly Kirshen1,2
1Division of Dermatology, Department of Medicine, The Ottawa Hospital, Ottawa, ON, Canada.
SAGE Open Medical Case Reports
|February 13, 2025
Summary
Abrocitinib effectively treated a patient with severe vulvar lichen planus resistant to other therapies. This Janus kinase 1 inhibitor significantly improved lesions and quality of life, offering a new treatment option.
Area of Science:
- Dermatology
- Immunology
- Pharmacology
Background:
- Vulvar lichen planus is a chronic inflammatory condition.
- It often presents with treatment-resistant variants, causing significant morbidity.
- Therapeutic goals include preventing scarring, squamous cell carcinoma, and managing symptoms like pruritus and pain.
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