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Updated: May 28, 2025

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Importance of the Study of the Right Heart Chambers in Symptomatic Acute Pulmonary Embolism
Nuria Rodríguez-Núñez1, Alejandra Virgós-Pedreira2, Alfonso Illade-Fornos3
1Servicio de Neumología Hospital Clínico-Universitario de Santiago Santiago de Compostela Spain.
Abstract:
We present the case of a 42-year-old woman on oral contraceptives that presented to the emergency department with pain and swelling in the left lower limb. Diagnosis of extensive deep vein thrombosis was established. A few minutes later, she exhibited signs of shock and hemodynamic instability, thus raising suspicion of high-risk acute pulmonary thromboembolism. Prior to the administration of fibrinolytic treatment, a bedside transthoracic echocardiography was performed that excluded right ventricular dilatation. Then, the study was complemented with a thoraco-abdominal computed tomography scan that demonstrated a large retroperitoneal hematoma as the cause of the shock. In conclusion, a transthoracic echocardiography should be performed before initiating thrombolytic therapy in hemodynamically instable patients with strong suspicion of high-risk pulmonary embolism.
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