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Hidden complexity of α7 nicotinic acetylcholine receptor desensitization revealed by MD simulations and Markov state

Mariia Avstrikova1, Paula Milán Rodríguez1, Sean M Burke2,3

  • 1Institut de Chimie de Strasbourg, UMR7177, CNRS, Université de Strasbourg, Strasbourg Cedex F-67083, France.

Proceedings of the National Academy of Sciences of the United States of America
|February 13, 2025
PubMed

Keywords:
MD simulationsMarkov-state modelingallosteric modulatorsdesensitizationnicotinic receptors

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