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Possible applications of the Polli dissolution mechanism: A case study using molecular dynamics simulation of

Peter J Skrdla1, Andrea Browning2, Shiva Sekharan3

  • 1Therapeutics Group, Schrödinger, Inc., 1540 Broadway, 24th Floor, New York, NY 10036, USA; Materials Science, Schrödinger, Inc., 1540 Broadway, 24th Floor, New York, NY 10036, USA; Department of Chemistry, Villanova University, 800 E. Lancaster Ave., Villanova, PA, 19085 USA.

Journal of Pharmaceutical Sciences
|February 13, 2025
PubMed

Keywords:
Dissolution modelDissolution rateDynamic simulationKineticsMechanistic modelingMolecular dynamicsSolubilityWater soluble

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