[Short and Long-Term Outcomes and Problems of Colorectal Cancer Surgery for Patients Aged 90 Years and Older]

In Japan, the fastest aging country in the world, colorectal cancer(CRC)patients at least 90 years old are rapidly increasing.

Among CRC patients who received resection of primary lesions between 2014 and 2023, we retrospectively compared and examined 24 cases of CRC aged 90 years or older(SE group)with non-elderly patients aged 50 to 74 years(NE group).

SE group had significantly poorer nutritional indexes and anemia. Right side colon cancer was more common in SE group. SE group patients were more frequently underwent laparotomy, and less D3 lymph node dissection. Therefore, operative time was significantly shorter in SE group. 3-year overall survival(OS)was significantly worse in SE group, but 3-year disease-specific survival(DSS)was comparable. Postoperative complication of Grade 2 or worse tended to occur more often in SE group, including cerebral infarction in 2 cases and heart failure in 1 case. The number of patients being discharged home was less frequent in SE group.

Patients with colorectal cancer aged 90 years or older had anemia and poorer nutritional indexes, and their OS was poor. We should pay attention to the possibility of postoperative including cerebral infarction and heart failure.