[A Case of a Solid Pseudopapillary Neoplasm (SPN) of the Pancreas, Resected Through Laparoscopy-A Case of Solid...

39-year-old woman with no significant medical history was found to have a pancreatic body tumor during abdominal ultrasound screening at our hospital. The ultrasound revealed a hypoechoic tumor with internal calcifications measuring 29×17 mm, displaying minimal internal vascularity. A contrast-enhanced CT scan characterized the lesion as a poorly enhancing solid tumor. Based on these findings, a suspicion of solid pseudopapillary neoplasm(SPN)of the pancreas was primary, leading to a laparoscopic spleen-preserving distal pancreatectomy. Pathologically, the tumor exhibited areas of solid and hemorrhagic necrosis, with irregularly interspersed hyaline stroma. Immunohistochemical staining showed diffuse positivity for vimentin, nuclear and cytoplasmic positivity for β-catenin, partial positivity for synaptophysin and CD10, and negativity for chromogranin A, bcl 10, and trypsin, confirming the diagnosis of SPN. This case report details the suspicion and successful laparoscopic surgical management of pancreatic SPN in a young female, reflecting on the radiological features and providing some brief literature review.