Related Experiment Video
Updated: May 28, 2025

Laparoscopic Radical Antegrade Modular Pancreatosplenectomy via Dorsal-Caudal Artery Approach for Pancreatic Neck-Body Cancer
Published on: November 18, 2022
[A Case of an Elderly Patient with Advanced Gastric Cancer, Who Underwent Safe Multimodality Treatment with
Shun Ito1, Shuhei Komatsu, Tomoki Konishi
1Dept. of Surgery, Japanese Red Cross Kyoto Daiichi Hospital.
Abstract:
Japanese prospective randomized trial of JCOG0405 showed that preoperative chemotherapy is one of useful treatment options for far-advanced gastric cancer patients with bulky and/or multiple lymph node metastases. Also, CheckMate649 and ATTRACTION-4 trials clarified the efficacy of immune-checkpoint inhibitor, nivolumab, in recurrent gastric cancer patients. Here, we presented an 87-year-old elderly female patient with far-advanced gastric cancer with bulky lymph nodes who was successfully treated by radical robotic gastrectomy following the low-dose preoperative chemotherapy, and achieved a complete response using nivolumab therapy after recurrences. In this case, the immunohistochemistry of cancer tissues suggested the microsatellite instability due to the deficiency of mismatch repair genes such as MLH1 and PSM2. Taken together, recent advances in chemotherapy and/or immunotherapy and minimally invasive surgery facilitate reasonable and personalized treatments even in super elderly patient with far-advanced gastric cancer.
More Related Videos
03:32Single Incision Plus One Port Laparoscopic Proximal Gastrectomy with Double Channel Anastomosis for Gastric Cancer Treatment
Published on: December 27, 2024
07:29Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Related Concept Videos
Nursing Ethical Principles II
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Peptic Ulcer Disease V: Surgical Management and Nursing Care
Surgical Interventions for Peptic Ulcer Disease
Tumor Immunotherapy