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Updated: May 28, 2025

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids
Published on: October 14, 2019
[A Clinicopathological Study of Nine Cases with Primary Small Bowel Adenocarcinoma]
Kengo Mohri1, Megumi Watanabe, Susumu Doita
1Dept. of Surgery, National Hospital Organization Iwakuni Clinical Center.
Abstract:
We analyzed the clinicopathological features and prognosis of 9 patients with primary small bowel adenocarcinoma, excluding duodenal cancer, between January 2009 and February 2024 at our hospital. The mean age of the patients was 68.9(60-82)years, and the male to female ratio was 7 : 2. Seven patients were diagnosed with small bowel cancer preoperatively, and 5 out of 7 patients were diagnosed pathologically. We performed partial resection in 6 patients and laparoscopic partial resection, laparoscopic ileocecal resection and endoscopic mucosal resection in 1 patient respectively. The histological type was well-differentiated adenocarcinoma in 6 patients, moderately differentiated adenocarcinoma in 1 patient, poorly differentiated adenocarcinoma in 2 patients. The pathological Stage was 0 in 2 patients, Stage Ⅱ in 3 patients, Stage Ⅲ in 3 patients, Stage Ⅳ in 1 patient. The median duration of follow-up was 18(1-143)months. Six patients are alive without recurrence, 1 patient died of cancer, and 2 patients died of other diseases. It was assumed that proactive radical surgery and postoperative adjuvant chemotherapy were associated with improved prognosis.

