[A Case of Cronkhite-Canada Syndrome Associated with Transverse Colon Cancer]

An 86-year-old man with a 3 months history of weight loss and bloody diarrhea was admitted to our hospital. Endoscopic examination revealed transverse colon cancer, along with numerous polypoid lesions in the stomach, duodenum, colon, and rectum. These findings led to a diagnosis of Cronkhite-Canada syndrome(CCS). Due to advanced colon cancer with stenosis, the patient underwent laparoscopic extended right hemicolectomy of the colon with D3 lymphadenectomy. The patient had no major postoperative complications and was discharged on the 17th postoperative day. Six weeks after surgery, the patient was treated with steroids, which led to an improvement in his symptoms. However, after the steroid dose was reduced, diarrhea worsened and the patient continued to receive treatment. The typical treatment for CSS is medical use of corticosteroids, but there is a timing issue regarding when to perform surgery on a patient with cancer. In this case, we could perform surgery for CCS with advanced colon cancer and safely introduce steroid therapy early after surgery.