[A Case of Successful FOLFOXIRI Therapy for Simultaneous Multiple Liver Metastases and Para-Aortic Lymph Node...

Advances in chemotherapy have improved the treatment of highly advanced colorectal cancer. Even patients with unresectable tumors with distant metastases to other organs can now be treated with chemotherapy alone and have a favorable prognosis of several years. However, a complete response to chemotherapy is rare. We report this case because of its rarity, as complete remission was maintained after primary resection and chemotherapy. The patient was a 52-year-old man who was admitted to a local hospital because of abdominal pain and diarrhea that had persisted for more than 1 month. Thoracoabdominal CT revealed lesions in the transverse colon, multiple ring-shaped lesions in the liver, and a mass around the aorta. The diagnosis was unresectable colorectal cancer with multiple liver and periaortic lymph node metastases. The patient underwent primary resection of the colorectal cancer and colostomy due to obstruction caused by the colorectal cancer. After 4 courses, CR and 12 courses of total were administered. The patient received 12 courses of total, followed by maintenance therapy. Currently, 25 months have passed since the start of chemotherapy and the patient is maintaining CR.