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Are Neurocognitive Deficits Associated With Gastrointestinal Symptoms in Children due to COVID-19?

Kalliopi Megari1,2, Evanthia Thomaidou3, Maria Eleni Palioura2

  • 1Department of Psychology, City College, University of York, Europe Campus, Thessaloniki, Greece.

International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience
|February 14, 2025
PubMed

Insights

Children with COVID-19 and gastrointestinal symptoms may face neurocognitive issues. Early detection of these symptoms is key for faster recovery and improved cognitive function in children.

Area of Science:

  • Pediatric Neurocognition
  • Infectious Disease Research
  • Gastroenterology

Background:

  • COVID-19 can lead to neurocognitive deficits in children, including concentration and memory problems.
  • These deficits may stem from the virus directly or from pandemic-related stress.
  • Gastrointestinal (GI) symptoms are a noted manifestation of COVID-19 in pediatric populations.

Purpose of the Study:

  • To investigate the impact of gastrointestinal symptoms on neurocognitive status in children with COVID-19.
  • To determine if GI symptoms in pediatric COVID-19 patients are associated with cognitive impairments.

Main Methods:

  • A comparative study involving 65 children diagnosed with COVID-19.
  • The study group comprised 32 children with GI symptoms and 33 children without GI symptoms.
  • Neurocognitive status was assessed and compared between the two groups.

Main Results:

  • A significant correlation was observed between the presence of GI symptoms and cognitive function in children with COVID-19.
  • The severity of GI symptoms was also significantly related to the degree of cognitive impairment.
  • Children with COVID-19 and GI symptoms are at higher risk for memory and other cognitive deficits.

Conclusions:

  • Gastrointestinal symptoms in pediatric COVID-19 cases are linked to neurocognitive deficits.
  • Early identification and intervention strategies are crucial for improving cognitive outcomes.
  • Prompt management can facilitate faster recovery of typical cognitive functioning in affected children.
Abstract

Keywords:
COVID‐19 patientsdiarrhoeadigestive systemgastrointestinal symptomspsychological factors

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