Neurotrophic Keratitis Following Vitrectomy Surgery: A Case Report

Area of Science:

• Ophthalmology
• Corneal Diseases
• Diabetic Retinopathy

Background:

• Neurotrophic keratitis is a degenerative corneal disorder linked to reduced sensory innervation, impairing epithelial healing.
• Patients with diabetes and prior herpes infections are at higher risk.
• This case involves a 60-year-old female with type 2 diabetes and a history of herpes infection.

Observation:

• The patient developed neurotrophic keratitis after ocular surgery for proliferative diabetic retinopathy.
• Initial treatment for infectious keratitis was unsuccessful, leading to a revised diagnosis.
• Persistent epithelial defects were observed despite initial interventions.

Findings:

• Management with autologous serum drops led to partial resolution of the epithelial defect.
• A central leucoma and significantly reduced visual acuity remained post-treatment.
• The case underscores the challenges in managing complex corneal conditions.

Implications:

• Early and accurate diagnosis of neurotrophic keratitis is essential.
• Targeted therapeutic strategies are critical for preventing irreversible corneal damage.
• Identifying and managing high-risk patient profiles can improve outcomes in corneal disease.