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A Case of Nocardia kroppenstedtii Infection Successfully Treated With a Multidisciplinary Approach
Francesco Foglia1, Annalisa Ambrosino1, Giuseppe Greco1
1Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.
Abstract:
Nocardia species constitute a diverse group of microorganisms classified as aerobic actinomyces. Among these species, many have been implicated as causative agents of severe human infections, particularly in immunocompromised patients, affecting lungs, skin, and nervous system. Here, we described a rare species, identified as Nocardia kroppenstedtii, isolated at the Complex Operative Unit of Virology and Microbiology from the subxiphoid formation and pseudonodular formation in the left leg of a 69-year-old immunocompetent patient, who was hospitalized and treated at the Complex Operative Unit of Internal Medicine and Geriatrics of the University Hospital of Campania "Luigi Vanvitelli" in an antimicrobial diagnostic stewardship context. This rare pathogen was first isolated in 2014 from a bronchoalveolar lavage sample obtained from a lung transplant recipient. Since then, only five cases of clinical interest have been described in literature.
Insights
This study reports a rare Nocardia kroppenstedtii infection in an immunocompetent patient, highlighting the pathogen
Area of Science:
- Microbiology
- Infectious Diseases
- Clinical Diagnostics
Background:
- Nocardia species are aerobic actinomyces known to cause severe infections, especially in immunocompromised individuals.
- Nocardia kroppenstedtii is a rare pathogen, first identified in 2014, with limited documented clinical cases.
- Infections can affect the lungs, skin, and nervous system.
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