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Updated: May 28, 2025

Author Spotlight: Exploring the Antibacterial Effects of Zinc Oxide Nanoparticles in Overcoming Antibiotic Resistance
Published on: September 27, 2024
Preparation and performance analysis of zinc-iron-based nanomaterials for targeted transport
Wenwen Cheng1, Jin Zhang1, Na Lin1
1Binzhou Vocational College, Binzhou, China.
Background:
Nanomaterials have applications in traditional Chinese medicine in the fields of medical equipment manufacturing, targeted transportation, and drug synergistic therapy.
Objective:
The research aims to discuss the performance and performance of zinc-iron-based nanomaterials in medical drug delivery and synergistic drug therapy.
Methods:
Using Prussian materials as precursors, magnetic zinc-iron nanomaterials were prepared by ZnCl2 and K3[Fe (CN)6]. Moreover, the morphology and composition of the material were analyzed.
Results:
X-ray analysis was conducted on the prepared Zn3[Fe (CN)6]2·xH2O nanomaterials, and their purity met the design requirements. At the same time, drug loading analysis was conducted on Zn3[Fe(CN)6]2·xH2O, and the release of capsaicin reached 86.3% under a certain phosphate buffer solution. Meanwhile, Zn3[Fe (CN)6]2·xH2O loaded tetracycline could release up to 90% in phosphate buffer solution. Antibacterial tests were conducted on self-made Zn3[Fe(CN)6]2·xH2O samples and ZnFe2O4/ZnO. The Zn3[Fe(CN)6]2·xH2O samples showed a more significant inhibitory effect on cancer cells after loading with capsaicin.
Conclusion:
The zinc-iron-based nanomaterials prepared by the research have excellent performance in drug loading and safety, indicating their significant potential for development in the medical field.

