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Published on: August 23, 2022
Meckel's diverticulum with ectopic pancreatic and epididymal tissue in a newborn infant
Sana Ahuja1, Shaivy Malik1, Sufian Zaheer1
1Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Introduction And Importance:
Meckel's diverticulum is a congenital anomaly affecting about 2 % of the population due to incomplete omphalomesenteric duct closure during fetal development. While often asymptomatic, it can cause complications like obstruction and bleeding. Ectopic tissue within the diverticulum, such as gastric and pancreatic tissue, is reported. This report presents a unique case of ectopic pancreatic and epididymal tissue in a newborn's Meckel's diverticulum, emphasizing the significance of histopathological examination.
Case Presentation:
A term male newborn presented with abdominal distension and bilious vomiting shortly after birth. Physical examination revealed a palpable abdominal mass. Ultrasound showed a dilated bowel loop with a blind-ending tubular structure suggestive of Meckel's diverticulum. Surgical resection identified a diverticulum 30 cm from the ileocecal valve. Histological examination confirmed ectopic pancreatic and epididymal tissue within the diverticulum.
Clinical Discussion:
The coexistence of ectopic pancreatic and epididymal tissue in Meckel's diverticulum is extremely rare. The embryological mechanism remains unclear, likely involving aberrant cell differentiation. Differential diagnosis in neonates with similar symptoms includes volvulus and Hirschsprung's disease. Imaging and histopathology are crucial for diagnosis. This case underscores the diverse ectopic tissue potential in Meckel's diverticulum and the importance of thorough evaluation.
Conclusion:
Ectopic tissue in Meckel's diverticulum should be considered in differential diagnoses of neonatal abdominal obstruction. Awareness and timely surgical intervention are vital for management.
Insights
This case report details a rare instance of ectopic pancreatic and epididymal tissue found in a newborn’s Meckel’s diverticulum. Early diagnosis and surgical intervention are crucial for managing neonatal abdominal obstruction.
Area of Science:
- Pediatric Surgery
- Congenital Anomalies
- Histopathology
Background:
- Meckel's diverticulum, a congenital anomaly from incomplete omphalomesenteric duct closure, affects ~2% of the population.
- While often asymptomatic, it can lead to complications like obstruction and bleeding.
- Ectopic tissues, including gastric and pancreatic, are occasionally found within Meckel's diverticulum.
Observation:
- A term male newborn presented with abdominal distension and bilious vomiting.
- Ultrasound revealed a structure suggestive of Meckel's diverticulum.
- Surgical resection and subsequent histological examination confirmed ectopic pancreatic and epididymal tissue within the diverticulum.
Findings:
- The coexistence of ectopic pancreatic and epididymal tissue in Meckel's diverticulum is exceptionally rare.
- The embryological origin of this dual ectopic tissue is currently unclear.
- Histopathological examination is critical for definitive diagnosis.
Implications:
- This case highlights the diverse range of ectopic tissues that can occur in Meckel's diverticulum.
- Ectopic tissue in Meckel's diverticulum must be considered in the differential diagnosis of neonatal abdominal obstruction.
- Prompt surgical intervention is vital for effective management and improved patient outcomes.
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