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Life's Essential 8 and Cardiovascular Disease in Breast Cancer Survivors

Kamari C Ositelu1, Tejasvi Peesay2, Carol Garcia2

  • 1Division of Cardiovascular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, 676 N. St. Clair, Suite 600, Chicago, IL, 60611, USA.

Current Cardiology Reports
|February 15, 2025
PubMed

Insights

Optimal cardiovascular health, defined by Life's Essential 8, may reduce cancer mortality in breast cancer survivors. Achieving ideal cardiovascular health offers significant benefits, guiding clinicians in managing survivor health risks.

Area of Science:

  • Cardiovascular Health
  • Oncology
  • Public Health

Background:

  • Breast cancer survivors face increased risks for cardiovascular disease (CVD) and cancer recurrence.
  • Cardiovascular health is increasingly recognized as a critical factor in cancer outcomes.

Purpose of the Study:

  • To explore the role of optimal cardiovascular health, as defined by the Life's Essential 8 (LE8), in breast cancer survivors.
  • To assess the potential benefits of achieving ideal cardiovascular health for this population.

Main Methods:

  • Review of current literature on cardiovascular health metrics and breast cancer outcomes.
  • Analysis of the components of the Life's Essential 8 framework.

Main Results:

  • Optimal cardiovascular health may be linked to reduced cancer mortality.
  • Breast cancer survivors may benefit from achieving ideal cardiovascular health.
  • Specific LE8 components (physical activity, smoking avoidance, lipid and blood pressure control) show benefits.

Conclusions:

  • The Life's Essential 8 serves as a valuable tool for clinicians to assess and manage breast cancer survivor health risks.
  • Further research is needed on the impact of anti-hyperglycemic agents, BMI, and sleep on CVD risk in survivors.
Abstract

Keywords:
Breast cancerBreast cancer survivorsCardiovascular diseaseLife’s essential eight

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