Association of a 97 kilodalton glycoprotein with human ovarian carcinoma

The association of a 97 kilodalton glycoprotein (97k-GP) with human ovarian epithelial tumors is reported. The 97k-GP has been found to be present in elevated levels in all the 8 serous cystadenocarcinoma specimens tested. This glycoprotein is present in small amounts in endometrial tumors and either absent or present in trace amounts in control ovaries. Subcellular localization of this glycoprotein indicates that it is a component of plasma membrane.