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Associated Factors for Erectile Dysfunction Occurrence in Patients with Coronary Artery Disease: A Cross-sectional

Ali Hamidi Madani1, Fardin Mirbolouk2, Mona Naghshbandi2

  • 1Urology Research Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Iranian Journal of Medical Sciences
|February 17, 2025
PubMed

Insights

Coronary artery disease (CAD) severity, older age, and higher body mass index (BMI) predict erectile dysfunction (ED) in men. These factors, along with others, contribute to ED development in patients with heart conditions.

Area of Science:

  • Cardiology
  • Urology
  • Public Health

Background:

  • Erectile dysfunction (ED) is linked to cardiovascular events.
  • Men with coronary artery disease (CAD) often show early ED signs.
  • Shared risk factors exist for both ED and CAD.

Purpose of the Study:

  • To identify risk factors and conditions in CAD patients contributing to ED.
  • To investigate the association between CAD severity and ED.
  • To determine predictors of ED in a CAD patient cohort.

Main Methods:

  • Analytical cross-sectional study in North Iran (Oct 2016 - Sep 2017).
  • 316 coronary artery disease patients enrolled.
  • International Index of Erectile Function (IIEF-15) used for ED assessment; logistic regression analyzed associated factors.

Main Results:

  • 55.1% of CAD patients had ED.
  • Higher CAD severity (OR=4.11) and more complex arterial involvement (OR=3.74) increased ED risk.
  • Age (OR=1.23) and BMI (OR=1.26) were independent predictors of ED.

Conclusions:

  • CAD severity, older age, and higher BMI are independent predictors of ED in CAD patients.
  • Diabetes, dyslipidemia, and smoking were not independent risk factors but could contribute to ED development.
  • Understanding these predictors can aid in managing ED in cardiovascular patients.
Abstract

Keywords:
Coronary angiographyCoronary artery diseaseErectile dysfunctionRisk factors

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