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Dilated Cardiomyopathy and Hyperthyroidism: A Case Report and Literature Review
Oussama Elgharnati1, Ikram Damoune1,2, Abdelmajid Chraibi1,2
1Department of Endocrinology and Metabolic Diseases, Centre Hospitalier Universitaire (CHU) Souss Massa, Agadir, MAR.
Abstract:
Dilated cardiomyopathy (DCM) is a rare but potentially reversible complication of hyperthyroidism, often resulting from severe thyrotoxicosis, leading to ventricular dilatation and reduced systolic function. A 45-year-old patient presented with progressive dyspnea and peripheral edema. Laboratory tests and imaging confirmed hyperthyroidism-induced DCM with a reduced ejection fraction (30%). Treatment with carbimazole and propranolol resulted in the normalization of thyroid function and cardiac recovery within three months. Hyperthyroidism can induce cardiac remodeling through genomic and non-genomic mechanisms of thyroid hormones, leading to reversible DCM. Early diagnosis and management are essential to avoid long-term complications, as delayed treatment may result in irreversible myocardial damage. This case highlights the need for multidisciplinary collaboration.
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