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Related Concept Videos

Vitamins01:30

Vitamins

543
Vitamins, derived from the Latin word for life, are essential organic substances required in small quantities for optimal growth and overall well-being. Unlike other organic nutrients, vitamins don't act as sources of energy or building materials but rather facilitate these nutrients' utilization by the body. Vitamins are predominantly coenzymes, assisting enzymes in specific chemical actions, like the oxidation of glucose for energy involving B vitamins. Most vitamins are not produced...
543
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

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Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

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Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
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Role of Vitamins in Maintaining Bone Health01:25

Role of Vitamins in Maintaining Bone Health

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
Vitamin A
Vitamin A is involved in the process of bone remodeling. Retinoic acid, the active metabolite of Vitamin A, has nuclear receptors in osteoblasts and osteoclasts, which are involved in bone remodeling.
Vitamin B12
Vitamin B12 acts as a cofactor during the formation of osteoblast-related proteins, such as osteocalcin. Vitamin B12 plays a role...
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Role of Neurotransmitters in Memory01:23

Role of Neurotransmitters in Memory

390
Neurotransmitters are integral to the brain's communication system, enabling neurons to transmit signals across synapses. This chemical exchange underpins various cognitive functions, including memory processes. The role of neurotransmitters in memory is multifaceted, influencing the encoding, consolidation, and retrieval of memories through their action on different neural circuits.
 Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
390
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

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Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
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Related Experiment Video

Updated: May 27, 2025

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
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Cognitive Decline and Vitamins.

Sneha Baxi Srivastava1

  • 1Skills Education, Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA (SBS).

American Journal of Lifestyle Medicine
|February 17, 2025
PubMed
Summary

Research on vitamin B and vitamin E for dementia and cognitive decline is ongoing. While current treatments manage symptoms, understanding the complex causes and effective interventions remains a key scientific challenge.

Area of Science:

  • Neurology
  • Nutritional Science

Background:

  • Dementia and cognitive decline present significant challenges due to their complexity and lack of cures.
  • Current treatments primarily manage symptoms and lack definitive cures, with ongoing research into underlying causes.
  • A vast body of literature exists, but much non-scientific advice lacks robust empirical support.

Purpose of the Study:

  • To review existing data on the role of vitamin B and vitamin E in dementia and cognitive decline.
  • To provide an evidence-based overview of these vitamins in the context of neurodegenerative conditions.

Main Methods:

  • Literature review of scientific articles.
  • Analysis of data concerning vitamin B and vitamin E interventions.
  • Focus on empirical evidence related to cognitive health.
Keywords:
alzheimer'scognitive declinedementiavitamin Bvitamin Evitamins

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Last Updated: May 27, 2025

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Main Results:

  • The review examines the current scientific understanding of vitamin B and E's impact on dementia.
  • Identifies gaps in knowledge regarding the efficacy and mechanisms of these vitamins.
  • Highlights the need for further rigorous research.

Conclusions:

  • Vitamin B and E are subjects of interest in dementia research, but conclusive evidence for their therapeutic role is still developing.
  • Further investigation is required to establish definitive links and effective therapeutic strategies.
  • Distinguishing evidence-based findings from anecdotal recommendations is crucial for managing cognitive decline.