Pediatric ocular tuberculosis: a case report of complex clinical manifestations and its successful management

Affannul Hakim1,2, Evelyn Komaratih1,2, Ismi Zuhria1,2

  • 1Department of Ophthalmology, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

PubMed

Insights

Ocular tuberculosis in children can cause severe vision loss. Prompt diagnosis and aggressive treatment with anti-tuberculosis drugs and corticosteroids are crucial for recovery.

Area of Science:

  • Ophthalmology
  • Pediatrics
  • Infectious Diseases

Background:

  • Ocular tuberculosis (TB) in children presents unique challenges compared to adults.
  • It often co-occurs with extrapulmonary TB and can lead to severe visual impairment.

Observation:

  • A 10-year-old girl experienced worsening eye redness and blurred vision.
  • She was diagnosed with ocular TB, including phlyctenular conjunctivitis, interstitial keratitis, scleritis, uveitis, and neuroretinitis.

Findings:

  • Antituberculosis therapy combined with corticosteroids and neuroprotection led to significant improvement within one month.
  • Full resolution was achieved after two months of treatment.

Implications:

  • Children's heightened inflammatory response to ocular TB necessitates aggressive corticosteroid therapy.
  • Early diagnosis and comprehensive management are vital to prevent vision loss in pediatric ocular TB.

Related Concept Videos

Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
168
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
210
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
218
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
128
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
293
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
2.5K