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Related Experiment Video

Updated: May 27, 2025

Building An Open-source Robotic Stereotaxic Instrument
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Optical coherence tomography guided automatic robotic craniotomy surgery platform.

Haoyuan Li1, Yongchao Wang1, Wei Chen1

  • 1Department of Biomedical Engineering, Southern University of Science and Technology, Shenzhen 518055, China.

Biomedical Optics Express
|February 17, 2025
PubMed
Summary

This study introduces an automated craniotomy platform using optical coherence tomography (OCT) and a precision drill. The system achieves a 100% success rate for creating transparent cranial windows for advanced brain imaging.

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Area of Science:

  • Neurosurgery
  • Biomedical Engineering
  • Optical Imaging

Background:

  • Transparent craniotomy windows are crucial for optical brain imaging.
  • Traditional methods are surgeon-dependent, time-consuming, and have low success rates.

Purpose of the Study:

  • To develop an automated platform for precise craniotomies.
  • To improve the efficiency and success rate of creating cranial windows for brain research.

Main Methods:

  • Integration of optical coherence tomography (OCT) for 3D skull imaging.
  • Development of a closed-loop, high-precision automated drilling system.
  • Creation of transparent craniotomy windows using a synthetic material.

Main Results:

  • Achieved a 100% success rate in creating various craniotomy window sizes and thicknesses.
  • Demonstrated high-quality OCT angiography, velocimetry, and ultrasound imaging through the windows.
  • The automated system proved efficient and reliable.

Conclusions:

  • The automated craniotomy platform offers a significant advancement for optical brain imaging.
  • This technology enhances the accessibility and quality of in-vivo brain research.
  • It provides a reliable and efficient solution for creating transparent cranial access.