Related Experiment Video
Updated: May 27, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
Published on: March 1, 2024
Gut microbiota on anxiety and depression in primary Sjogren's syndrome: A novel insight
Ying Zhu1, Kaiyuan Zhang2, Ziyue Luo1
1The Second Clinical Medical College of Zhejiang Chinese Medical University, Hangzhou, China.
Abstract:
Primary Sjogren's syndrome (pSS) is a prevalent disease in rheumatology and immunology. Anxiety, depression, and other mood disorders are pervasive across diverse sectors of society. Recent theories on the gut-brain axis have elucidated that the gut microbiota considered the second brain of humans, can modulate the central nervous system and behavior by mediating bidirectional response systems, including immunity, vagus nerve, and neuroendocrine pathways. This article reviews recent advancements that explore the mechanism between gut microbiota and emotional disorders in pSS. It aims to provide novel therapies for these emotional disorders in pSS.
More Related Videos
Related Concept Videos
Irritable Bowel Syndrome I: Introduction
IBS is a chronic condition that can persist over a long period or recur frequently.
The pathogenesis of IBS involves a complex interplay of the following factors:
Altered...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
Generalized Anxiety Disorder

