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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Carbohydrate Metabolism01:36

Carbohydrate Metabolism

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Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
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Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Updated: May 27, 2025

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
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Life Lessons and Diabetes Research.

Paula M Trief1

  • 1Department of Psychiatry and Behavioral Sciences, State University of New York Upstate Medical University, Syracuse, NY.

Diabetes Spectrum : a Publication of the American Diabetes Association
|February 17, 2025
PubMed
Summary

Dr. Trief received the 2024 Richard R. Rubin Award for groundbreaking behavioral research in diabetes care. The award highlights significant contributions to understanding diabetes across diverse populations.

Area of Science:

  • Behavioral science
  • Diabetes research
  • Public health

Background:

  • The American Diabetes Association (ADA) annually recognizes leading researchers.
  • Behavioral aspects of diabetes significantly impact patient outcomes.
  • Diverse populations present unique challenges in diabetes management.

Purpose of the Study:

  • To acknowledge outstanding contributions in behavioral diabetes research.
  • To highlight innovative approaches to understanding diabetes in varied communities.
  • To emphasize the importance of behavioral science in diabetes care.

Main Methods:

  • Award recipient selection based on innovative research contributions.
  • Focus on research addressing behavioral aspects of diabetes.

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  • Consideration of impact across diverse patient populations.

    • Main Results:

    • Dr. Trief honored with the 2024 Richard R. Rubin Award.
    • Recognition of Dr. Trief's significant and innovative work.
    • Emphasis on the value of behavioral research in diabetes.

    Conclusions:

    • Behavioral research is crucial for advancing diabetes care.
    • Innovative approaches are needed to address diabetes in diverse groups.
    • Continued focus on the behavioral aspects of diabetes is essential.