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Updated: Jul 19, 2026

Whole Vitreous Humor Dissection for Vitreodynamic Analysis
Published on: May 24, 2015
Estimation of Vitreous Chamber Volume Using Axial Length Measurements
Yihong Huang1, Yan Zhang1, Wanzhu Chen1
1Department of Ophthalmology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China; Department of Ophthalmology, Second Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian Province, China and Engineering Research Centre of Assistive Technology for Visual Impairment, Fujian Province University.
Background:
Vitreous chamber volume (VCV) in humans can be accurately measured using magnetic resonance imaging (MRI) combined with ITK-SNAP analysis software. This study explores the relationship between VCV and axial length (AL).
Methods:
This study included 46 healthy individuals, encompassing a total of 92 eyes. Individuals with a history of eye conditions were excluded from the study. AL measurements were obtained using the Lenstar 900 (Haag-Streit, Switzerland). VCV was assessed through MRI using the Ingenia 3.0T system (Philips Medical Systems, Netherlands), with VCV analysis performed using ITK-SNAP analysis software version 3.8.0. The correlation between AL and VCV was evaluated using Pearson linear correlation coefficient, and a logistic regression model was employed to predict VCV.
Results:
The sample consisted of 92 eyes from 46 individuals, including 28 women and 18 men. The average VCV was 6193±1135.9 mm 3 for women and 6324.3±886.7 mm 3 for men. The mean AL for women was 24.70±2.78 mm, while for men it was 24.66±1.70 mm. A significant correlation between AL and VCV was observed ( P <0.001).
Conclusions:
VCV can be accurately estimated through AL measurements, offering a clinically relevant method for assessing VCV.
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