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Pharmacogenomic (PGx) testing is increasingly used in healthcare. This tutorial details the University of Florida Health

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Area of Science:

  • Genomic Medicine
  • Clinical Informatics
  • Pharmacogenomics

Background:

  • Pharmacogenomic (PGx) testing has gained prominence for predicting drug response over the past decade.
  • Clinical decision support (CDS) is crucial for integrating PGx results into clinical practice and educating prescribers.
  • The Epic Genomics module facilitates the storage of structured genomic data and PGx CDS implementation.

Purpose of the Study:

  • To outline the implementation process of the Epic Genomics module at University of Florida Health.
  • To identify critical success factors for integrating PGx CDS into electronic health records.

Main Methods:

  • The University of Florida Health Precision Medicine Program implemented the Epic Genomics module.
  • The tutorial details the specific steps and strategies employed during the deployment.
  • Key factors for successful integration were identified through the implementation experience.

Main Results:

  • Successful deployment of the Epic Genomics module in early 2022.
  • Established a framework for integrating PGx testing into routine clinical workflows.
  • Identified best practices for utilizing electronic health record tools for PGx CDS.

Conclusions:

  • The implementation of the Epic Genomics module is feasible and beneficial for healthcare institutions.
  • Effective PGx CDS integration requires careful planning and execution.
  • The University of Florida Health experience provides a valuable model for other institutions seeking to adopt PGx testing.