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Successful lung transplantation in RPILD associated with anti-MDA5ab+: A case report
Chaoyang Zhang1, Jianxing Guo, Guowei Ye
1Department of Intensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin, China.
Rationale:
Lung transplantation in rapidly progressive interstitial lung disease associated with antimelanoma differentiation-associated gene 5 antibody positive may be a rescue therapy in case of medical treatment failure and impossible weaning from the ventilatory support.
Patient Concerns:
A 59-year-old man with cough, expectoration, and fever for more than half a month, which aggravated with dyspnea for 4 days.
Diagnoses:
Rapidly progressive interstitial lung disease was confirmed through chest high-resolution computed tomography and antimelanoma differentiation-associated gene 5 antibody positive.
Interventions:
The patient was given extracorporeal membrane oxygenation and double lung transplantation.
Outcomes:
The patient is currently undergoing rehabilitation in a general ward and follow-up.
Lessons:
Lung transplantation should be considered when impossible weaning from the ventilatory support.
