Recent advances in localized surface plasmon resonance (LSPR) sensing technologies

Area of Science:

• Optics and Photonics
• Nanotechnology
• Biosensing

Background:

• Localized Surface Plasmon Resonance (LSPR) is an optical phenomenon in noble metal nanostructures.
• LSPR generates sharp spectral absorption peaks and enhanced local electromagnetic fields.
• These properties are widely exploited in chemical and biological sensing applications.

Purpose of the Study:

• To provide an overview of recent advancements in Localized Surface Plasmon Resonance (LSPR) sensor technology.
• To highlight the development of various LSPR sensing modalities.
• To discuss the integration of emerging technologies with LSPR sensors.

Main Methods:

• Review of refractive-index sensing based on resonant wavelength shifts.
• Exploration of molecular sensing via colorimetry and imaging techniques.
• Analysis of LSPR sensor integration with micro/nano fluidics and artificial intelligence (AI).

Main Results:

• LSPR sensors offer a label-free analytical method with rapidly developing capabilities.
• Diverse sensing strategies, including refractive-index, colorimetric, and imaging, have been established.
• Integration with microfluidics and AI enhances LSPR sensor functionality and performance.

Conclusions:

• LSPR sensor technology has seen significant progress, offering versatile sensing platforms.
• The combination of LSPR with advanced techniques like AI promises further improvements in sensitivity and application scope.
• LSPR sensors represent a powerful tool for label-free chemical and biological analysis.